Of the following human aneuploidies, which is the one that generally has the most severe impact on the health of the individual?

Of the following human aneuploidies, which is the one that generally has the most severe impact on the health of the individual? 




A) 47, +21
B) 47, XXY
C) 47, XXX
D) 47, XYY
E) 45, X







Answer: A


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